On Twitter, officers confirmed the incident was centred on Usher Road in Bow and they are asking for the public to stay away from the area.
The tweet read: “Emergency Response Team are dealing with a serious incident in Usher Road, E3, and surrounding streets.
“Please avoid the area if possible.”
Police confirmed a woman is being treated in a London hospital after sustaining a serious head injury.
They tweeted they are investigating the circumstances of the incident.
Unconfirmed reports say it was a shooting.
A Met Office spokesperson said: “Police were called by London Ambulance Service at approximately 6.10pm on Tuesday, November 24 to reports of a woman suffering a head injury in Usher Road.
“Her condition is not life threatening.”
Tower Hamlets Police have since confirmed there have been no arrests at this time.
They tweeted: “Police were called by London Ambulance Service at approximately 18:10hrs on Tuesday, 24 November to reports of a woman suffering a head injury in Usher Road, E3.
“Her condition is not life threatening.
“Enquiries are underway to establish how she came to be injured. No arrests.”
This is a breaking story… More to follow.