All traffic was stopped on the clockwise carriageway between J16 for Salford and Kearsley and J17 for Whitefield and Prestwich during rush hour.
Police and traffic officers rushed to the scene at about 4.20pm.
Highways England North West said on Twitter: “The #M60 clockwise #J16 (#Salford #Kearsley) to #J17 (#Whitefield #Prestwich #A56) traffic has been temporarily STOPPED due to an incident.
“@gmptraffic @NWmwaypolice & Traffic Officers are on their way to the area.”
North West Motorway Police added: “Clockwise and Anticlockwise carriageways closed on M60 between j17 and j16 while Police deal with incident, please be patient.”
Stopping the traffic has caused long delays in the area, according to traffic alert service Inrix.
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